Yes, it is possible to create data groups that wrap over column (vertical) and row (horizontal) I/Os from adjacent sides on a Stratix® IV device in the Quartus® II software version 9.0. Enable this functionality by using a Quartus II ini variable.
If one does not exist, create a text file called quartus.ini in your project directory and add the following text:
tgx_allow_mem_interface_wrap_around_corner = on
The Quartus II software must be re-started before the ini variable is effective.
Future versions of the Quartus II software will support hybrid interfaces for Stratix IV devices without the need for the ini variable.